Published July 12, 1991.
Name of Drug
Colae semen, cola nut.
Composition of Drug
Cola nut consists of the endosperm freed from the testa of various Cola species Schott et Endlicher, particularly C. nitida (Ventenat) Schott et Endlicher [Fam. Sterculiaceae], as well as its preparations in effective dosage.
The drug contains at least 1.5 percent methylxanthine (caffeine, theobromine).
Uses
Mental and physical fatigue.
Contraindications
Gastric and duodenal ulcers.
Side Effects
Sleep disorders, over-excitability, nervous restlessness, and gastric irritations may occur.
Interactions with Other Drugs
Strengthening of the action of psychoanaleptic drugs and caffeine-containing beverages.
Dosage
Unless otherwise prescribed:
Daily dosage:
- 2 - 6 g cola nut (Erg. B. 6);
- 0.25 - 0.75 g cola extract (Erg. B. 6);
- 2.5 - 7.5 g cola liquid extract (Erg. B. 6);
- 10 - 30 g cola tincture (Erg. B. 6);
- 60 - 180 g cola wine (Erg. B. 6).
Mode of Administration
Powdered drug and other galenical preparations for internal use.
Actions
From animal experiments:
- Analeptic
- Stimulates production of gastric acid
- Lipolytic
- Increases motility
In humans:
- Compared to methylxanthine, caffeine is a weaker diuretic and positively chronotropic.
* Source: German Commission E Monographs (Phytotherapy)
- base of phytotherapeutic drug approval by the german health administration -
